In the article, the researchers used molecular staining techniques to identify several mutations in colon cancer that are common on stem cells from a single tumor, producing fluorescent barcodes.
At the critical moment, the newborn is very sensitive to the effects of mutations in intestinal stem cells, which will unwittingly seed a large number of precancerous variations in their intestines (a process is known as canceration area), thus increasing the risk of neonatal disease. To know about cell staining kit visit https://www.bosterbio.com/products/cell-staining-kits.html
When transported to mice, the fluorescent petiole cells can be effectively tracked, revealing the dynamics of precancerous cellular and molecular events.
Researchers have discovered a key difference in the generation of mutant cells in the tissues of precancerous intestinal occupancy infants and adults.
Mutated cells will grow and spread, which can not be detected by current screening techniques. Of course, these numbers are generally harmless, but if relevant, they can develop into cancer as an adult.
According to a recent report published in Nature Communications, researchers from Duke University and other institutions showed how stem cell mutation occurs silently and spread to many regions of the large intestine until they ultimately dominate and develop into a malignant tumor.
By using innovative system models in mice, researchers were able to visually mark the colon cancer mutation by raising stem cell fluorescence, and then they can observe mutations in colon disease in animals and explain the intestinal tract.
And it can clarify the process of death to death that occurs in the intestines. One mutation will address other mutations and eventually became the driving energy for malignant tumors.